THE EFFECT OF GIVING CRUDE EXTRACT OF PURSLANE TOPICALLY TO ACCELERATE THE 2nd GRADE OF BURN HEALING PROCESS IN GUINEA PIGS

Oktaffrastya, W.S and Sudiana, I. Ketut and Wahyuni, Erna Dwi (2016) THE EFFECT OF GIVING CRUDE EXTRACT OF PURSLANE TOPICALLY TO ACCELERATE THE 2nd GRADE OF BURN HEALING PROCESS IN GUINEA PIGS. In: The Proceeding of 7th International Nursing Conference: Global Nursing Challenges in The Free Trade Era, 8-9 April 2016, Surabaya.

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Official URL: http://ners.unair.ac.id

Abstract

Introduction Burns can be treated either chemically or naturally. Purslane is one of the herbs that are useful for healing wound because it has a lot of advantages like antimycrobacterium, increasing fibroblast cell proliferation and collagen synthesis. Aim this research to explain the effect of giving crude extract of purslane to accelerate the second grade of burn wound healing process in guinea pigs. Method This research using a true-experimental design by 20 samples, 3 months old-male guinea pigs, divided into two groups, 1 treatment group and 1 control group. This classification was done randomize. Data obtained from the observation of the signs both of inflammatory and proliferation phase. Mann-Whitney statistical test used to analyze erythema and edema inflammatory phase. While wound fluid, wound granulation, and wound side using non-parametric statistical test namely Kruskal-Wallis. Result Result showed that there were differences between crude extract of purslane and control group in erythema (p=0.028), wound granulation (p=0.057) and wound side (p=1.000) at 3rd day, erythema (p=0.028), wound granulation (p=0.028) and wound side (p=1.000) at 5th day, and erythema (p=1.000), wound granulation (p=0.027) and wound side (p=0.029) at 7th day. Discussion In conclusion, crude extract of purslane was proven to be more effectives in accelerated burn wound grade 2nd healing, increasing fibroblast cell proliferation and reduce any infection risks. For further research, microscopic observation of collagen, PMN-cell (neutrophile), MN-cell (Lymphocyte and monocyte) is needed. Keyword: purslane, Portulaca oleracea L., burn wound healing

Item Type: Conference or Workshop Item (Poster)
Subjects: R Medicine > RT Nursing
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Dimas Dwi Arbi
Date Deposited: 09 Nov 2016 12:21
Last Modified: 09 Nov 2016 12:21
URI: http://eprints.ners.unair.ac.id/id/eprint/363

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